Epidemologische Studie über Prostatakrebs
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Animal foods, protein, calcium and prostate cancer risk: the European Prospective Investigation into Cancer and Nutrition\"
Also hier ist der Originaltext:
\"Abstract
We examined consumption of animal foods, protein and calcium in relation to risk of prostate cancer among 142 251 men in the European Prospective Investigation into Cancer and Nutrition. Associations were examined using Cox regression, stratified by recruitment centre and adjusted for height, weight, education, marital status and energy intake. After an average of 8.7 years of follow-up, there were 2727 incident cases of prostate cancer, of which 1131 were known to be localised and 541 advanced-stage disease. A high intake of dairy protein was associated with an increased risk, with a hazard ratio for the top versus the bottom fifth of intake of 1.22 (95% confidence interval (CI): 1.07–1.41, Ptrend=0.02). After calibration to allow for measurement error, we estimated that a 35-g day-1 increase in consumption of dairy protein was associated with an increase in the risk of prostate cancer of 32% (95% CI: 1–72%, Ptrend=0.04). Calcium from dairy products was also positively associated with risk, but not calcium from other foods. The results support the hypothesis that a high intake of protein or calcium from dairy products may increase the risk for prostate cancer.\"
Quelle:
Epidemiology
British Journal of Cancer (2008) 98, 1574–1581. doi:10.1038/sj.bjc.6604331
http://www.nature.com/bjc/journal/v98/n9/abs/6604331a.html
Hier sind die teilnehmenden Staaten und Institutionen der Krebsstudie aufgelistet:
\"Animal foods, protein, calcium and prostate cancer risk: the European Prospective Investigation into Cancer and Nutrition
N E Allen1, T J Key1, P N Appleby1, R C Travis1, A W Roddam1, A Tjønneland2, N F Johnsen2, K Overvad3, J Linseisen4, S Rohrmann4, H Boeing5, T Pischon5, H B Bueno-de-Mesquita6, L Kiemeney7,8, G Tagliabue9, D Palli10, P Vineis11,12, R Tumino13, A Trichopoulou14, C Kassapa14, D Trichopoulos15, E Ardanaz16, N Larrañaga17, M-J Tormo18, C A González19, J R Quirós20, M-J Sánchez21, S Bingham22, K-T Khaw23, J Manjer24, G Berglund25, P Stattin26, G Hallmans27, N Slimani28, P Ferrari28, S Rinaldi28 and E Riboli12
1Cancer Epidemiology Unit, University of Oxford, Oxford, UK
2Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
3Department of Epidemiology and Social Medicine, University of Aarhus, Aarhus, Denmark
4Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
5German Institute of Human Nutrition, Potsdam-Rehbücke, Germany
6National Institute of Public Health and Environment, Bilthoven, The Netherlands
7Department of Epidemiology, University Medical Centre, Nijmegen, The Netherlands
8Department of Urology, University Medical Centre, Nijmegen, The Netherlands
9Lombardy Cancer Registry Unit, National Cancer Institute, Milan, Italy
10Molecular and Nutritional Epidemiology Unit, Scientific Institute of Tuscany, Florence, Italy
11Department of Biomedical Science, University of Turin, Turin, Italy
12Department of Epidemiology and Public Health, Imperial College, London, UK
13Cancer Registry, Azienda Ospedaliera Civile M.P. Arezzo, Ragusa, Italy
14Department of Hygiene and Epidemiology, University of Athens Medical School, Athens, Greece
15Hellenic Health Foundation, Athens, Greece
16Seccion de Vigilancia y Control Epidemiologico, Instituto de Salud Publica de Navarra, Pamplona, Spain
17Epidemiology Unit, Basque Health Department in Gipuzkoa, San Sebastian, Spain
18Epidemiology Department, Murcia Health Council, Murcia, Spain
19Catalan Institute of Oncology, Barcelona, Spain
20Public Health and Health Planning Directorate, Asturias, Spain
21Andalusian School of Public Health, Granada, Spain
22MRC Centre for Nutritional Epidemiology in Cancer Prevention and Survival, Department of Public Health and Primary Care, Cambridge, UK
23Department of Gerontology, University of Cambridge, Cambridge, UK
24Department of Surgery, Malmö University Hospital, Lund University, Malmö, Sweden
25Department of Clinical Sciences, Malmö University Hospital, Lund University, Malmö, Sweden
26Division of Urology and Andrology, Department of Surgical and Perioperative Sciences, Umeå University Hospital, Umeå, Sweden
27Department of Public Health and Clinical Medicine, Nutrition Research, Umeå University Hospital, Umeå, Sweden
28Nutrition and Hormones Group, International Agency for Research on Cancer, Lyon, France\"
[url]
http://www.nature.com/bjc/journal/v98/n9/abs/6604331a.html[/url]
- Editiert von Juliane am 04.08.2008, 12:11 -